Polyvinyl alcohol (PVA) is a water-soluble polymer material widely used in the preparation of hemostatic fibers, artificial skin, plasma substitutes, etc. It can also be used as a drug sustained-release carrier material to prepare targeted microspheres. Animal experiments have shown that it is completely harmless and has good biocompatibility. It can be slowly degraded in the body, so it is widely used as a drug carrier. Polyvinyl alcohol microspheres with a particle size of less than 10 microns release drugs into the human body to achieve the purpose of treatment and immunity. For example, PVA microspheres made of erythropoietin, interferon, and cholera toxin B subunit can be absorbed orally. Through dispersion polymerization, polyvinyl alcohol microspheres with a size of 1-10μm can be prepared, and they can also be further chemically converted into various types of functionalized microspheres according to the different requirements of the application field.
Polyvinyl alcohol foam embolic microspheres are medical substances used for embolization of blood vessels. They are mainly composed of polyvinyl alcohol and/or polyglycolide and are specially treated to enable them to swell and embolize blood vessels. Such microparticles are often used in intravascular surgery to prevent blood from flowing into and contaminating the surgical area. In addition, they can also be used to treat ischemic stroke and other vascular diseases.
Features of polyvinyl alcohol foam embolic microspheres include: it can swell upon contact with blood and quickly solidify, thereby effectively embolizing blood vessels. The microspheres are degradable and will be absorbed by the body after a period of time, which helps reduce the risk of complications. In addition, it can be combined with other substances (such as drugs) to achieve specific therapeutic purposes. When using polyvinyl alcohol foam embolic microspheres, strict guidelines and standard operating procedures need to be followed. These microspheres are usually inserted into blood vessels by medical professionals when using endovascular procedures.
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